ORIGINAL: Prevalence and Clinical Characteristics of Coronavirus Disease 2019 Seen at a Testing Centre in Lagos Nigeria.

West Afr J Med. 2021 Jan; 38(1): 54-58. PMID: 33463708

Authors

  • A. O. Salako Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.
  • O. S. Amoo Centre for Human Virology and Genomics, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.
  • O. O. Odubela Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.
  • K. A. Osuolale Monitoring and Evaluation Unit, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.
  • A. B. James Biochemistry and Nutrition Department, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.
  • D. A. Oladele Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.
  • A. Z. Musa Monitoring and Evaluation Unit, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.
  • F. A. Ige Centre for Human Virology and Genomics, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.
  • A. P. Okwuraiwe Centre for Human Virology and Genomics, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.
  • C. K. Onwuamah Centre for Human Virology and Genomics, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.
  • J. O. Shaibu Centre for Human Virology and Genomics, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.
  • A. N. David Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.
  • R. A. Audu Centre for Human Virology and Genomics, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.
  • O. C. Ezechi Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.
  • N. N. Odunukwe Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.
  • B. L. Salako Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria and College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria.

Keywords:

SARS-CoV-2, COVID-19, NIMR, Clinical, Prevalence

Abstract

Background: The SARS-CoV-2 infection continues to ravage the global community since it was declared a pandemic. The socio-demographic and clinical characteristics defining the disease are mainly from Europe and Asia. The disease symptomatology is similar to the prevalent diseases in our environment, this could result in the delay in prompt identification and appropriate management of suspected cases toward combating community transmission. This study evaluates the prevalence, socio-demographic and clinical characteristics of positive cases of COVID -19.

Methods: This was a retrospective cohort study. Data on the socio-demographic, clinical characteristics and the results of the SARS-CoV-2 test of participants at the Nigerian Institute of Medical Research [NIMR] Modified Drive-through Centre for COVID-19 test sample collection over two months [24th February 2020- 27th April 2020] were retrieved from the electronic medical records (EMR). Data obtained were analyzed using SPSS version 22.0.

Results: A total number of 481 clients were evaluated in this review. The prevalence of SARS-CoV-2 infection in the population was 14.6%. The mean age of the positive cases was 42.2 [±15.9] years. The common symptoms reported by the positive cases were fever (40.0%), cough (32.9%), sore throat (17.1%) and running nose (15.7%). Fever depicted statistical significance with positive cases with the majority being of mild to moderate clinical severity.

Conclusion: The prevalence of SARS-CoV-2 infection among this cohort was 14.6% with a male preponderance. Fever and sore throat were the variables that predicted SARS CoV-2 infection among our cohort.

Published

2021-01-31

Issue

Vol. 38 No. 1 (2021): The West African Journal of Medicine

Section

Articles
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