Odontogenic Tumours: A Clinicopathologic Appraisal of Cases seen in a Nigerian Tertiary Hospital using 2017 WHO Classification

A. C. Oluwarotimi, O. M. Ogundana, O. M. Gbotolorun, O. James, O. Adebule

Abstract

BACKGROUND: Odontogenic tumours (OT) are a group of
diverse lesions seen in the maxillofacial region. They are
categorized according to their tissues of origin as; epithelial,
mesenchymal or mixed tumours.

OBJECTIVES: The aim of this study is to present the
proportion of odontogenic tumours seen in Lagos University
Teaching Hospital using the 2017 WHO classification.

METHODS: Data from cases of OT histologically diagnosed
from January 2006 to December 2016 were collected from records
of the Oral and Maxillofacial Surgery and Oral and Maxillofacial
Pathology Departments. Information on age, sex, site of
occurrence and histologic diagnosis were recorded. After
reconfirmation of diagnosis, cases were categorized according
to the latest World Health Organization (WHO) classification
for OT. Ethical approval was obtained and data was analyzed
using SPSS software for Windows (version 22: SPSS, Chicago
IL).

RESULTS: A total of 232 odontogenic tumours were diagnosed
during the period of study, 227(97.8%) cases were benign OT
and 82.8% occurred in the mandible. The mean age ± SD of
patients was 32.1±13.8 years and the age range from 2–73 years.
OT was slightly more common in females (119) with an almost
equal male-to-female ratio of 1:1.1. Most of the patients were in
the 21–30 year age group and ameloblastoma 148(63.8%) was
the most common OT. The histological types of odontogenic
tumours and the age group of patients were significantly
associated with the site of occurrence of tumours (P=0.000*
and P=0.037* respectively).

CONCLUSION: Epithelial odontogenic tumours are still by
far the most common odontogenic tumours. WAJM 2023;
40(9): 914–919.

Keywords: Odontogenic tumours, Classification of
odontogenic tumours, Epidemiology.